LGALS13

LGALS13, also known as galectin-13, is a protein encoded by the corresponding gene. It is also commonly referred to as placental protein 13 (PP13). Galectin-13 specifically binds to β-galactosides and is involved in cell - cell and cell - matrix interactions. It participates in the TGF - β signaling pathway, which is crucial for cell growth, differentiation, and apoptosis.
Abnormal expression of LGALS13 is associated with pre - eclampsia and other pregnancy - related disorders. In drug development, targeting galectin - 13 is being explored as a potential therapeutic approach for these diseases. Research efforts aim to develop drugs that can modulate its function to improve pregnancy outcomes.