LSS

The input "LSS" refers to lanosterol synthase, an enzyme encoded by the LSS gene. It catalyzes the cyclization of (S)-2,3-oxidosqualene to form lanosterol, a key step in cholesterol biosynthesis. Common aliases include squalene epoxide cyclase.
LSS functions in the mevalonate pathway, regulating cholesterol production. Mutations may link to congenital cataracts or hypotrichosis. Research explores its role in cholesterol-related disorders, with potential for therapeutic targeting in metabolic diseases, though specific drug development remains preliminary.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LSS Antibody (CSB-PA013216ESR1HU)

Validated Data

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA013216ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA013216ESR1HU at dilution of 1:100

The following LSS reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

LSS Antibodies

LSS Proteins

LSS Antibodies

LSS Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA013216GA01HU	LSS Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA013216ESR1HU	LSS Antibody	Human	ELISA, IHC
CSB-PA013216ESR2HU	LSS Antibody	Human	ELISA, WB, IHC

LSS Proteins

LSS Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP013216HU CSB-BP013216HU CSB-MP013216HU CSB-EP013216HU-B	Recombinant Human Lanosterol synthase (LSS)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP013216HU	Recombinant Human Lanosterol synthase (LSS)	E.coli

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LSS

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