Mitogen-activated protein kinase 7 is a protein in humans that is encoded by MAPK7 gene. Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
The following MAPK7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MAPK7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013465GA01HU | MAPK7 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA013465ESR1HU | MAPK7 Antibody |
Human | ELISA, IHC, IF |
CSB-PA080162 | MAPK7 Antibody |
Human,Mouse,Rat | WB, IHC |
CSB-PA080163 | MAPK7 Antibody |
Human,Mouse,Rat | WB, IHC |
CSB-PA556658 | MAPK7 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA905442 | MAPK7 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
MAPK7 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP013465RA CSB-EP013465RA CSB-BP013465RA CSB-MP013465RA CSB-EP013465RA-B |
Recombinant Rat Mitogen-activated protein kinase 7 (Mapk7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK7 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP013465BO CSB-EP013465BO CSB-BP013465BO CSB-MP013465BO CSB-EP013465BO-B |
Recombinant Bovine Mitogen-activated protein kinase 7 (MAPK7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK7 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP013465MO CSB-EP013465MO CSB-BP013465MO CSB-MP013465MO CSB-EP013465MO-B |
Recombinant Mouse Mitogen-activated protein kinase 7 (Mapk7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP013465HU CSB-EP013465HU CSB-BP013465HU CSB-MP013465HU CSB-EP013465HU-B |
Recombinant Human Mitogen-activated protein kinase 7 (MAPK7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |