MAS1, Proto-oncogene Mas, alias MAS, MGRA. MAS1 is encoded by the human MAS1 gene, which is located on chromosome 6 in the q25.3 region. The protein encoded by MAS1 is a class I, seven-transmembrane G-protein-coupled receptor for angiotensin-(1-7) that preferentially couples to Gq proteins and activates the phospholipase C signaling pathway.
MAS1 plays a role in several processes, including hypotension, smooth muscle relaxation, and cardioprotection, by mediating the actions of angiotensin-(1-7). MAS1, as a G protein-coupled receptor, is involved in the regulation of blood pressure and cardiovascular function, and also plays an important role in tumorigenesis, development, and positive regulation of DNA replication.
MAS1 Antibody (CSB-PA013505LA01HU)
Validated Data
Western Blot
Positive WB detected in:U251 whole cell lysate, A375 whole cell lysate
All lanes: MAS1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa
Immunofluorescence staining of Hela cell with CSB-PA013505LA01HU at 1:180, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunofluorescence staining of Hela cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
The following MAS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MAS1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013505ESR2HU | MAS1 Antibody | Human | ELISA, IHC |
CSB-PA080177 | MAS1 Antibody | Human,Mouse,Rat | WB, IHC |
CSB-PA013505LA01HU | MAS1 Antibody | Human | ELISA, WB, IF |
CSB-PA013505LB01HU | MAS1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA084695 | MAS1 Antibody | Human,Mouse,Rat | ELISA,IHC |
MAS1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018243XA01SVG | MAS1 Antibody | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ELISA, WB (ensure identification of antigen) |
MAS1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Source |
---|---|---|
CSB-YP018243SVG CSB-EP018243SVG CSB-BP018243SVG CSB-MP018243SVG CSB-EP018243SVG-B |
Recombinant Saccharomyces cerevisiae Mitochondrial-processing peptidase subunit beta (MAS1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAS1 Proteins for Agrobacterium rhizogenes
Code | Product Name | Source |
---|---|---|
CSB-YP329763AEW CSB-EP329763AEW CSB-BP329763AEW CSB-MP329763AEW CSB-EP329763AEW-B |
Recombinant Agropine synthesis reductase (mas1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP343063AEW CSB-EP343063AEW CSB-BP343063AEW CSB-MP343063AEW CSB-EP343063AEW-B |
Recombinant Agropine synthesis reductase (mas1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAS1 Proteins for Agrobacterium tumefaciens (strain 15955)
Code | Product Name | Source |
---|---|---|
CSB-YP344637AEZ CSB-EP344637AEZ CSB-BP344637AEZ CSB-MP344637AEZ CSB-EP344637AEZ-B |
Recombinant Agrobacterium tumefaciens Agropine synthesis reductase (mas1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAS1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF013505RA | Recombinant Rat Proto-oncogene Mas (Mas1) | in vitro E.coli expression system |
CSB-YP013505RA1 CSB-EP013505RA1 CSB-BP013505RA1 CSB-MP013505RA1 CSB-EP013505RA1-B |
Recombinant Rat Proto-oncogene Mas (Mas1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAS1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF013505MO | Recombinant Mouse Proto-oncogene Mas (Mas1) | in vitro E.coli expression system |
CSB-YP013505MO1 CSB-EP013505MO1 CSB-BP013505MO1 CSB-MP013505MO1 CSB-EP013505MO1-B |
Recombinant Mouse Proto-oncogene Mas (Mas1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAS1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF013505HU | Recombinant Human Proto-oncogene Mas (MAS1) | in vitro E.coli expression system |
CSB-YP013505HU1 CSB-EP013505HU1 CSB-BP013505HU1 CSB-MP013505HU1 CSB-EP013505HU1-B |
Recombinant Human Proto-oncogene Mas (MAS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |