MFGE8

MFGE8, also known as Milk fat globule-EGF factor 8 protein, is a peripheral membrane glycoprotein with diverse functions. It plays a crucial role in the phagocytosis of apoptotic cells, facilitating their clearance by macrophages. MFGE8 interacts with phosphatidylserine on the surface of apoptotic cells and integrins on macrophages, triggering signal transduction pathways that enhance phagocytosis. This protein is involved in inflammatory responses and inflammatory/autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis. Research on MFGE8 has led to potential therapeutic strategies, including the development of inhibitors and drugs targeting the protein to modulate its function in these diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MFGE8 Antibody (CSB-PA07974A0Rb)

Validated Data

Western Blot
Positive WB detected in: Mouse skeletal muscle tissue
All lanes: MFGE8 antibody at 1.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 44, 32, 38, 39 kDa
Observed band size: 44 kDa

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA07974A0Rb at dilution of 1:100

Human milk fat globule-EGF factor 8 protein(MFGE8) ELISA kit (CSB-E12637h)

Validated Data

Code: CSB-E12637h

Size: 96T,5×96T,10×96T

Sensitivity: 195.31 pg/mL

Detection Range: 781.25 pg/mL-50000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following MFGE8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MFGE8 Antibodies

MFGE8 Proteins

MFGE8 ELISA Kits

MFGE8 Antibodies

MFGE8 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-MA079741A0m	MFGE8 Monoclonal Antibody	Human	ELISA,IHC
CSB-PA07974A0Rb	MFGE8 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA07974D0Rb	MFGE8 Antibody, Biotin conjugated	Human	ELISA
CSB-PA07974B0Rb	MFGE8 Antibody, HRP conjugated	Human	ELISA

MFGE8 Proteins

MFGE8 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP013752RA CSB-BP013752RA CSB-MP013752RA CSB-EP013752RA-B	Recombinant Rat Lactadherin (Mfge8)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MFGE8 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP013752PI CSB-BP013752PI CSB-MP013752PI CSB-EP013752PI-B	Recombinant Pig Lactadherin (MFGE8)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MFGE8 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP013752MO CSB-EP013752MO CSB-BP013752MO CSB-MP013752MO CSB-EP013752MO-B	Recombinant Mouse Lactadherin (Mfge8)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MFGE8 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP839153BO CSB-EP839153BO CSB-BP839153BO CSB-MP839153BO CSB-EP839153BO-B	Recombinant Bovine Lactadherin (MFGE8)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MFGE8 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-BP013752HU CSB-MP013752HU CSB-EP013752HU-B	Recombinant Human Lactadherin (MFGE8)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP013752HU	Recombinant Human Lactadherin (MFGE8)	E.coli

MFGE8 ELISA Kit

MFGE8 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E12637h	Human milk fat globule-EGF factor 8 protein(MFGE8) ELISA kit	serum, cell culture supernates, urine, cerebrospinal fluid (CSF)	195.31 pg/mL

MFGE8 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL013752MO	Mouse Lactadherin(MFGE8) ELISA kit	serum, plasma, tissue homogenates	7.8 pg/mL

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Popular Pathways

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MFGE8

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