MS4A7

The gene MS4A7 encodes a protein known as membrane-spanning 4-domains A7, which is a member of the membrane-spanning 4A gene family. This protein is characterized by its transmembrane structure and is involved in various cellular processes, including signal transduction and immune function. MS4A7 is commonly referred to as CD20L4 or 4SPAN2. It interacts with other proteins in the CD20/Fc-epsilon-RIbeta family, and its expression is associated with late-onset Alzheimer's disease. Research into MS4A7 is ongoing, with potential implications for drug development targeting neurodegenerative disorders and immune-related diseases.
In terms of signaling pathways, MS4A7 is linked to several important pathways, including those involved in inflammation and immune response. Its expression is regulated by various factors, and its dysregulation has been implicated in several diseases. Current drug development efforts are focused on identifying small molecules that can modulate MS4A7 function, with the aim of developing novel therapeutic strategies for diseases such as Alzheimer's and other inflammatory conditions.