MTA1

The protein corresponding to the gene name MTA1 is Metastasis Associated Protein 1, also commonly known as MTA-1. This protein is mainly involved in chromatin remodeling and gene transcription regulation through its interaction with the nucleosome remodeling and deacetylase (NuRD) complex. It participates in the MAPK and Wnt signaling pathways, which are crucial for cell growth and differentiation.
Abnormal expression of MTA1 is associated with various cancers, including breast, colorectal, and gastric cancers. In the field of drug development, there are ongoing efforts to design inhibitors targeting MTA1 to block tumor metastasis. However, more research is needed to translate these findings into effective clinical therapies.