MYL12A

MYL12A, also known as myosin light chain 12A, encodes a non-sarcomeric myosin regulatory light chain protein. This protein plays a crucial role in the contraction of smooth muscle and non-muscle cells. Its phosphorylation state can influence the activity of the actin complex, thereby modulating muscle contraction strength and cell movement speed. Consequently, MYL12A plays a significant role in various biological processes, including muscle contraction, cell division, and other vital activities. Moreover, recent studies have revealed that MYL12A plays an important role in multiple diseases. Its phosphorylation level is associated with heart diseases such as myocardial injury and hypertrophy, as well as cancer. Therefore, MYL12A holds promise as a potential research target and biomarker for diseases like heart disease and cancer.

Popular Product:

Recombinant Human Myosin regulatory light chain 12A (MYL12A) (Active)

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human MYL12A at 2μg/mL can bind Anti-MYL9 recombinant antibody (CSB-RA015318MA1HU)，the EC₅₀ is 5.325-6.456 ng/mL.