NCOA7

The protein encoded by NCOA7 is Nuclear Receptor Coactivator 7, commonly referred to as AMF1 or CIA. It functions as a transcriptional coactivator, interacting with nuclear receptors like estrogen receptor to modulate target gene expression involved in cell proliferation and differentiation.
NCOA7 is linked to signaling pathways such as MAPK and PI3K/Akt. Dysregulation is associated with breast cancer and neurodegenerative disorders. Current research explores its role as a potential therapeutic target, though specific drug candidates remain in preclinical stages.