NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 is a protein that in humans is encoded by the NDUFA4L2 gene. The NDUFA4L2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. The human NDUFA4L2 gene codes for a subunit of Complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. Initially, NADH binds to Complex I and transfers two electrons to the isoalloxazine ring of the flavin mononucleotide (FMN) prosthetic arm to form FMNH2. The electrons are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ), which is reduced to ubiquinol (CoQH2). The flow of electrons changes the redox state of the protein, resulting in a conformational change and pK shift of the ionizable side chain, which pumps four hydrogen ions out of the mitochondrial matrix.
The following NDUFA4L2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NDUFA4L2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015627GA01HU | NDUFA4L2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA563041 | NDUFA4L2 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA003385 | NDUFA4L2 Antibody |
Human,Mouse | WB, ELISA |
CSB-PA878874LA01HU | NDUFA4L2 Antibody |
Human | ELISA, IHC |
CSB-PA878874LB01HU | NDUFA4L2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA878874LD01HU | NDUFA4L2 Antibody, Biotin conjugated |
Human | ELISA |
NDUFA4L2 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP666177BO CSB-EP666177BO CSB-BP666177BO CSB-MP666177BO CSB-EP666177BO-B |
Recombinant Bovine NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NDUFA4L2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP675688MO CSB-EP675688MO CSB-BP675688MO CSB-MP675688MO CSB-EP675688MO-B |
Recombinant Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (Ndufa4l2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NDUFA4L2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP878874HU CSB-EP878874HU CSB-BP878874HU CSB-MP878874HU CSB-EP878874HU-B |
Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |