NPC2

Epididymal secretory protein E1 is a protein in humans that is encoded by NPC2 gene. Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE. NPC2 binds unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes and transfers it to the cholesterol-binding pocket of the N-terminal domain of NPC1.

The following NPC2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

NPC2 Antibodies

NPC2 Proteins

NPC2 Antibodies

NPC2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA015976GA01HU	NPC2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA015976LA01HU	NPC2 Antibody	Human	ELISA, IHC, IF
CSB-PA015976LD01HU	NPC2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA015976LC01HU	NPC2 Antibody, FITC conjugated	Human
CSB-PA015976LB01HU	NPC2 Antibody, HRP conjugated	Human	ELISA

NPC2 Antibodies for Dog

Code	Product Name	Species Reactivity	Application
CSB-PA634688LA01DO	NPC2 Antibody	Dog	ELISA
CSB-PA634688LC01DO	NPC2 Antibody, FITC conjugated	Dog

NPC2 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA194333XA01DOA	NPC2 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

NPC2 Antibodies for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Species Reactivity	Application
CSB-PA741621XA01DOT	NPC2 Antibody	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	ELISA, WB (ensure identification of antigen)

NPC2 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA619598XA01SVG	NPC2 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

NPC2 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA871642XA01SXV	npc2 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

NPC2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA872080XA01DIL	npc2 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

NPC2 Proteins

NPC2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP015976BO CSB-EP015976BO CSB-BP015976BO CSB-MP015976BO CSB-EP015976BO-B	Recombinant Bovine Epididymal secretory protein E1 (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP015976HU CSB-EP015976HU CSB-BP015976HU CSB-MP015976HU CSB-EP015976HU-B	Recombinant Human Epididymal secretory protein E1 (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP015976PI CSB-EP015976PI CSB-BP015976PI CSB-MP015976PI CSB-EP015976PI-B	Recombinant Pig Epididymal secretory protein E1 (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP015976EQV CSB-EP015976EQV CSB-BP015976EQV CSB-MP015976EQV CSB-EP015976EQV-B	Recombinant Pan troglodytes Epididymal secretory protein E1 (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP015976MOV CSB-EP015976MOV CSB-BP015976MOV CSB-MP015976MOV CSB-EP015976MOV-B	Recombinant Macaca fascicularis Epididymal secretory protein E1 (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)

Code	Product Name	Source
CSB-YP317308CTK CSB-EP317308CTK CSB-BP317308CTK CSB-MP317308CTK CSB-EP317308CTK-B	Recombinant Cryptococcus neoformans var. neoformans serotype D Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)

Code	Product Name	Source
CSB-YP317755CTL CSB-EP317755CTL CSB-BP317755CTL CSB-MP317755CTL CSB-EP317755CTL-B	Recombinant Cryptococcus neoformans var. neoformans serotype D Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP619598SVG CSB-EP619598SVG CSB-BP619598SVG CSB-MP619598SVG CSB-EP619598SVG-B	Recombinant Saccharomyces cerevisiae Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-EP634688DO	Recombinant Dog Epididymal secretory protein E1 (NPC2)	E.coli
CSB-BP634688DO CSB-MP634688DO CSB-EP634688DO-B	Recombinant Dog Epididymal secretory protein E1 (NPC2)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP634688DO	Recombinant Dog Epididymal secretory protein E1 (NPC)	Yeast
CSB-EP634688DOa2	Recombinant Dog Epididymal secretory protein E1 (NPC2)	E.coli

NPC2 Proteins for Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)

Code	Product Name	Source
CSB-YP680856UBS CSB-EP680856UBS CSB-BP680856UBS CSB-MP680856UBS CSB-EP680856UBS-B	Recombinant Ustilago maydis Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)

Code	Product Name	Source
CSB-YP682517EKF CSB-EP682517EKF CSB-BP682517EKF CSB-MP682517EKF CSB-EP682517EKF-B	Recombinant Emericella nidulans Phosphatidylglycerol/phosphatidylinositol transfer protein (npc2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Code	Product Name	Source
CSB-YP688458CZD CSB-EP688458CZD CSB-BP688458CZD CSB-MP688458CZD CSB-EP688458CZD-B	Recombinant Candida albicans Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

Code	Product Name	Source
CSB-YP700425NGS CSB-EP700425NGS CSB-BP700425NGS CSB-MP700425NGS CSB-EP700425NGS-B	Recombinant Neosartorya fumigata Phosphatidylglycerol/phosphatidylinositol transfer protein (npc2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)

Code	Product Name	Source
CSB-YP709567MPM CSB-EP709567MPM CSB-BP709567MPM CSB-MP709567MPM CSB-EP709567MPM-B	Recombinant Magnaporthe oryzae Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)

Code	Product Name	Source
CSB-YP715371DIS CSB-EP715371DIS CSB-BP715371DIS CSB-MP715371DIS CSB-EP715371DIS-B	Recombinant Debaryomyces hansenii Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)

Code	Product Name	Source
CSB-YP715454YAP CSB-EP715454YAP CSB-BP715454YAP CSB-MP715454YAP CSB-EP715454YAP-B	Recombinant Yarrowia lipolytica Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)

Code	Product Name	Source
CSB-YP738358KBK CSB-EP738358KBK CSB-BP738358KBK CSB-MP738358KBK CSB-EP738358KBK-B	Recombinant Kluyveromyces lactis Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

Code	Product Name	Source
CSB-YP738917CZI CSB-EP738917CZI CSB-BP738917CZI CSB-MP738917CZI CSB-EP738917CZI-B	Recombinant Candida glabrata Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Source
CSB-YP741621DOT CSB-EP741621DOT CSB-BP741621DOT CSB-MP741621DOT CSB-EP741621DOT-B	Recombinant Ashbya gossypii Phosphatidylglycerol/phosphatidylinositol transfer protein (NPC2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP871642SXV CSB-EP871642SXV CSB-BP871642SXV CSB-MP871642SXV CSB-EP871642SXV-B	Recombinant Schizosaccharomyces pombe Phosphatidylglycerol/phosphatidylinositol transfer protein (npc2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NPC2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP872080DIL CSB-EP872080DIL CSB-BP872080DIL CSB-MP872080DIL CSB-EP872080DIL-B	Recombinant Danio rerio Epididymal secretory protein E1 (npc2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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