Serine/threonine-protein kinase PAK 5 is a protein in humans that is encoded by PAK5 gene. Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
The following PAK5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PAK5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA017410GA01HU | PAK7 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA285604 | Phospho-PAK7/PAK6 (Ser602/Ser560) Antibody |
Human,Mouse | ELISA,WB |
CSB-PA265580 | PAK7 Antibody |
Human | ELISA,WB,IHC |
CSB-PA003702 | PAK7 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA164310 | PAK7 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA158224 | PAK7 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA885798ZA01HU | PAK5 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
PAK5 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP017410RA CSB-EP017410RA CSB-BP017410RA CSB-MP017410RA CSB-EP017410RA-B |
Recombinant Rat Serine/threonine-protein kinase PAK 7 (Pak7) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK5 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP805374MO CSB-EP805374MO CSB-BP805374MO CSB-MP805374MO CSB-EP805374MO-B |
Recombinant Mouse Serine/threonine-protein kinase PAK 7 (Pak7) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP885798HU(A4) CSB-MP885798HU CSB-EP885798HU(A4)-B |
Recombinant Human Serine/threonine-protein kinase PAK 5 (PAK5) |
Yeast Mammalian cell In Vivo Biotinylation in E.coli |