1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 is a protein in humans that is encoded by PLCD4 gene. Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
The following PLCD4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PLCD4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018132GA01HU | PLCD4 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA866264LA01HU | PLCD4 Antibody | Human | ELISA, IHC |
CSB-PA866264ESR1HU | PLCD4 Antibody | Human | ELISA, IHC, IF |
PLCD4 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP018132BO CSB-EP018132BO CSB-BP018132BO CSB-MP018132BO CSB-EP018132BO-B |
Recombinant Bovine 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP654888XBE CSB-EP654888XBE CSB-BP654888XBE CSB-MP654888XBE CSB-EP654888XBE-B |
Recombinant Xenopus laevis 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (plcd4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Code | Product Name | Source |
---|---|---|
CSB-YP689974MOV CSB-EP689974MOV CSB-BP689974MOV CSB-MP689974MOV CSB-EP689974MOV-B |
Recombinant Macaca fascicularis 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP723470RA CSB-EP723470RA CSB-BP723470RA CSB-MP723470RA CSB-EP723470RA-B |
Recombinant Rat 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (Plcd4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP732806PYX CSB-EP732806PYX CSB-BP732806PYX CSB-MP732806PYX CSB-EP732806PYX-B |
Recombinant Pongo abelii 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP811707MO CSB-EP811707MO CSB-BP811707MO CSB-MP811707MO CSB-EP811707MO-B |
Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (Plcd4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP840470PI CSB-EP840470PI CSB-BP840470PI CSB-MP840470PI CSB-EP840470PI-B |
Recombinant Pig 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLCD4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP866264HU CSB-BP866264HU CSB-MP866264HU CSB-EP866264HU-B |
Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP866264HU | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4) | E.coli |