Peptidyl-prolyl cis-trans isomerase F, mitochondrial is a protein in humans that is encoded by PPIF gene. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis.
The following PPIF reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PPIF Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018476GA01HU | PPIF Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA929434 | PPIF Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA001907 | PPIF Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA781876 | PPIF Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA903914 | PPIF Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA018476ESR1HU | PPIF Antibody | Human | ELISA, WB, IHC |
CSB-PA018476ESR2HU | PPIF Antibody | Human | ELISA, IHC |
PPIF Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP018476HU CSB-EP018476HU CSB-BP018476HU CSB-MP018476HU CSB-EP018476HU-B |
Recombinant Human Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPIF Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP018476RA CSB-EP018476RA CSB-BP018476RA CSB-MP018476RA CSB-EP018476RA-B |
Recombinant Rat Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Ppif) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPIF Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP018476BO CSB-EP018476BO CSB-BP018476BO CSB-MP018476BO CSB-EP018476BO-B |
Recombinant Bovine Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPIF Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP860377MO CSB-EP860377MO CSB-BP860377MO CSB-MP860377MO CSB-EP860377MO-B |
Recombinant Mouse Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Ppif) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |