Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential step that triggers RIG-I/DDX58-mediated signaling activation.
The following PPP6C reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PPP6C Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018583GA01HU | PPP6C Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA018583LA01HU | PPP6C Antibody |
Human | ELISA, IHC, IF |
CSB-PA018583LB01HU | PPP6C Antibody, HRP conjugated |
Human | ELISA |
CSB-PA018583LC01HU | PPP6C Antibody, FITC conjugated |
Human | |
CSB-PA018583LD01HU | PPP6C Antibody, Biotin conjugated |
Human | ELISA |
PPP6C Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP018583HU CSB-EP018583HU CSB-BP018583HU CSB-MP018583HU CSB-EP018583HU-B |
Recombinant Human Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP6C Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP720689RA CSB-EP720689RA CSB-BP720689RA CSB-MP720689RA CSB-EP720689RA-B |
Recombinant Rat Serine/threonine-protein phosphatase 6 catalytic subunit (Ppp6c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP6C Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP863425MO CSB-EP863425MO CSB-BP863425MO CSB-MP863425MO CSB-EP863425MO-B |
Recombinant Mouse Serine/threonine-protein phosphatase 6 catalytic subunit (Ppp6c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP6C Proteins for Dictyostelium discoideum (Slime mold)
Code | Product Name | Source |
---|---|---|
CSB-YP871372DKK CSB-EP871372DKK CSB-BP871372DKK CSB-MP871372DKK CSB-EP871372DKK-B |
Recombinant Dictyostelium discoideum Serine/threonine-protein phosphatase 6 catalytic subunit (ppp6c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |