PROCR

The protein encoded by the gene PROCR is known as Protein C Receptor, also referred to as EPCR (Epidermal Growth Factor Receptor Protein-C). This receptor is activated by the serine protease activated protein C (APC) and plays a crucial role in the blood coagulation pathway. Its mechanism involves the regulation of thrombin generation and the modulation of inflammation and endothelial cell function. PROCR is involved in various signaling pathways, including the ERK, PI3K–Akt–mTOR, and RhoA–ROCK pathways. Diseases associated with PROCR include thrombosis and inflammation-related disorders. In terms of drug development, research is ongoing to identify novel therapies that target PROCR for the treatment of these conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PROCR Antibody (CSB-PA06329A0Rb)

Validated Data

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA06329A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA06329A0Rb at dilution of 1:100

Western blot
All lanes: PROCR antibody at 2µg/ml + Mouse lung tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 27 kDa
Observed band size: 27 kDa

Human soluble endothelial protein C receptor,sEPCR ELISA Kit (CSB-E09901h)

Validated Data

Code: CSB-E09901h

Size: 96T,5×96T,10×96T

Sensitivity: 1.95 ng/mL

Detection Range: 7.8 ng/mL-500 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PROCR reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PROCR Antibodies

PROCR Proteins

PROCR ELISA Kits

PROCR Antibodies

PROCR Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA06329A0Rb	PROCR Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA018743GA01HU	PROCR Antibody	Human	ELISA,WB,IHC
CSB-PA005324	PROCR Antibody	Human,Mouse,Rat	WB, ELISA

PROCR Proteins

PROCR Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP636710BO CSB-EP636710BO CSB-BP636710BO CSB-MP636710BO CSB-EP636710BO-B	Recombinant Bovine Endothelial protein C receptor (PROCR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PROCR Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP709280RA CSB-EP709280RA CSB-BP709280RA CSB-MP709280RA CSB-EP709280RA-B	Recombinant Rat Endothelial protein C receptor (Procr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PROCR Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP717564MO CSB-EP717564MO CSB-BP717564MO CSB-MP717564MO CSB-EP717564MO-B	Recombinant Mouse Endothelial protein C receptor (Procr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PROCR Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP892160HU CSB-EP892160HU CSB-BP892160HU CSB-MP892160HU CSB-EP892160HU-B	Recombinant Human Endothelial protein C receptor (PROCR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP892160HU	Recombinant Human Endothelial protein C receptor (PROCR), partial	E.coli

PROCR ELISA Kit

PROCR ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E09901h	Human soluble endothelial protein C receptor,sEPCR ELISA Kit	serum, plasma, tissue homogenates	1.95 ng/mL

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PROCR

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