Protein-tyrosine kinase 2-beta is a protein in humans that is encoded by PTK2B gene. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress.
The following PTK2B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PTK2B Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018994GA01HU | PTK2B Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA146740 | Phospho-PTK2B (Tyr402) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA235151 | PTK2B (Ab-402) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA571474 | Phospho-PTK2B (Tyr579) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA213093 | PTK2B (Ab-579) Antibody | Human,Mouse | ELISA,WB |
CSB-PA003891 | PTK2B Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA008178 | Phospho-PTK2B (Y881) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008179 | Phospho-PTK2B (Y580) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008181 | Phospho-PTK2B (Y579) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008182 | Phospho-PTK2B (Y402) Antibody | Human,Mouse,Rat | IHC, ELISA |
CSB-PA008185 | PTK2B Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008187 | PTK2B Antibody | Human,Mouse,Rat | IHC, ELISA |
CSB-PA982747 | PTK2B Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA914875 | PTK2B Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA613494LA01HU | PTK2B Antibody | Human | ELISA, IHC, IF |
CSB-PA613494LB01HU | PTK2B Antibody, HRP conjugated | Human | ELISA |
CSB-PA613494LC01HU | PTK2B Antibody, FITC conjugated | Human | |
CSB-PA613494LD01HU | PTK2B Antibody, Biotin conjugated | Human | ELISA |
PTK2B Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP018994RA CSB-EP018994RA CSB-BP018994RA CSB-MP018994RA CSB-EP018994RA-B |
Recombinant Rat Protein-tyrosine kinase 2-beta (Ptk2b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTK2B Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP613494HU CSB-EP613494HU CSB-BP613494HU CSB-MP613494HU CSB-EP613494HU-B |
Recombinant Human Protein-tyrosine kinase 2-beta (PTK2B), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTK2B Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP868757MO CSB-EP868757MO CSB-BP868757MO CSB-MP868757MO CSB-EP868757MO-B |
Recombinant Mouse Protein-tyrosine kinase 2-beta (Ptk2b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |