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Tyrosine-protein phosphatase non-receptor type 2 is a protein in humans that is encoded by PTPN2 gene. Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the cytoplasm. Negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis. Plays a multifaceted and important role in the development of the immune system.
The following PTPN2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PTPN2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA019031GA01HU | PTPN2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
PTPN2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP019031HU CSB-EP019031HU CSB-BP019031HU CSB-MP019031HU CSB-EP019031HU-B |
Recombinant Human Tyrosine-protein phosphatase non-receptor type 2 (PTPN2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTPN2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP019031RA CSB-EP019031RA CSB-BP019031RA CSB-MP019031RA CSB-EP019031RA-B |
Recombinant Rat Tyrosine-protein phosphatase non-receptor type 2 (Ptpn2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
