Regulator of G-protein signaling 14 is a protein in humans that is encoded by RGS14 gene. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways.
The following RGS14 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
RGS14 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA019646GA01HU | RGS14 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA077027 | RGS14 Antibody |
Human | ELISA,WB |
CSB-PA006675 | RGS14 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA019646ESR1HU | RGS14 Antibody |
Human | ELISA, WB |
CSB-PA019646ESR2HU | RGS14 Antibody |
Human | ELISA, IHC |
RGS14 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP019646MO CSB-BP019646MO CSB-MP019646MO CSB-EP019646MO-B |
Recombinant Mouse Regulator of G-protein signaling 14 (Rgs14) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RGS14 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP019646RA CSB-EP019646RA CSB-BP019646RA CSB-MP019646RA CSB-EP019646RA-B |
Recombinant Rat Regulator of G-protein signaling 14 (Rgs14) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RGS14 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP019646HU CSB-EP019646HU CSB-BP019646HU CSB-MP019646HU CSB-EP019646HU-B |
Recombinant Human Regulator of G-protein signaling 14 (RGS14) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |