ROBO4, also known as Roundabout homolog 4, is a protein with several common aliases such as MGC16442 and SAX. Its main mechanism involves guiding angiogenesis and maintaining vascular stability by interacting with specific ligands. It is mainly involved in the Slit - Robo signaling pathway, which is crucial for vascular development.
Aberrations in ROBO4 are associated with various vascular - related diseases like diabetic retinopathy and certain types of cancer. In drug development, researchers are exploring agents that target ROBO4 to modulate angiogenesis, aiming to develop new therapies for conditions where abnormal blood vessel growth is a key factor.
Recombinant Human Roundabout homolog 4 (ROBO4), partial (CSB-EP845177HU1d7)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA903544(ROBO4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA903544(ROBO4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
Human Roundabout homolog 4(ROBO4) ELISA kit (CSB-EL020057HU)
Validated Data
Code: CSB-EL020057HU
Size: 96T,5×96T,10×96T
Sensitivity: 15.6 pg/mL
Detection Range: 62.5 pg/mL-4000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following ROBO4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ROBO4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020057GA01HU | ROBO4 Antibody | Human,Mouse | ELISA,WB |
CSB-PA121728 | ROBO4 Antibody | Human | ELISA,IHC |
CSB-PA903544 | ROBO4 Antibody | Human | ELISA,IHC |
CSB-PA845177ESR2HU | ROBO4 Antibody | Human | ELISA, IHC |
ROBO4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP845177HU CSB-EP845177HU CSB-BP845177HU CSB-MP845177HU CSB-EP845177HU-B |
Recombinant Human Roundabout homolog 4 (ROBO4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP845177HU1d7 | Recombinant Human Roundabout homolog 4 (ROBO4), partial | E.coli |
ROBO4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL020057HU | Human Roundabout homolog 4(ROBO4) ELISA kit | serum, plasma, tissue homogenates, cell culture supernates, urine | 15.6 pg/mL |