Nuclear receptor ROR-alpha is a protein in humans that is encoded by RORA gene. Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target genes regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts.
The following RORA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
RORA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020069GA01HU | RORA Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA004020 | RORA Antibody |
Human,Monkey | WB, IHC, IF, ELISA |
CSB-PA182231 | RORA Antibody |
Human | ELISA,WB |
CSB-PA020069LA01HU | RORA Antibody |
Human, Mouse | ELISA, WB |
CSB-PA020069LB01HU | RORA Antibody, HRP conjugated |
Human | ELISA |
CSB-PA020069LC01HU | RORA Antibody, FITC conjugated |
Human | |
CSB-PA020069LD01HU | RORA Antibody, Biotin conjugated |
Human | ELISA |
RORA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP020069HU CSB-MP020069HU CSB-EP020069HU-B |
Recombinant Human Nuclear receptor ROR-alpha (RORA) |
E.coli Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP020069HU1(F1) | Recombinant Human Nuclear receptor ROR-alpha (RORA),Partial |
Yeast |
CSB-EP020069HUa0 | Recombinant Human Nuclear receptor ROR-alpha (RORA) |
E.coli |
CSB-BP020069HU | Recombinant Human Nuclear receptor ROR-alpha (RORA) |
Baculovirus |
RORA Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP020069MO CSB-EP020069MO CSB-BP020069MO CSB-MP020069MO CSB-EP020069MO-B |
Recombinant Mouse Nuclear receptor ROR-alpha (Rora) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |