RPRD1B

RPRD1B encodes the RNA polymerase II C-terminal domain phosphatase-like protein 1B. It's also known as RPAP2. Function-wise, RPRD1B is crucial for regulating RNA polymerase II activity, influencing transcription initiation and elongation. It participates in various signaling pathways related to gene expression control.
Abnormalities in RPRD1B are associated with certain cancers, such as leukemia. Research is underway to develop drugs that target RPRD1B to disrupt the abnormal signaling in cancer cells. These drugs aim to correct gene - expression patterns and potentially offer new therapeutic options for related diseases.