SLC38A9

SLC38A9, formally solute carrier family 38 member 9 (alias SNAT9), is a lysosomal membrane transporter mediating arginine and glutamine transport. It acts as a critical amino acid sensor for the mTORC1 pathway: upon binding arginine, it interacts with Rag GTPases and Ragulator, activating mTORC1 to regulate cell growth, proliferation, and autophagy.
Dysregulation of SLC38A9 links to mTORC1-related disorders like renal cell carcinoma and metabolic syndromes. Preclinical studies explore small-molecule inhibitors targeting SLC38A9 to modulate mTORC1 signaling, offering potential cancer and metabolic disease therapies, though no drugs are yet clinically approved.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SLC38A9 Antibody (CSB-PA836713LA01HU)

Validated Data

Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: SLC38A9 antibody at 3.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 64, 53, 57 kDa
Observed band size: 64 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA836713LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA836713LA01HU at dilution of 1:100

Immunofluorescent analysis of U251 cells using CSB-PA836713LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following SLC38A9 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SLC38A9 Antibodies

SLC38A9 Proteins

SLC38A9 Antibodies

SLC38A9 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA836713LA01HU	SLC38A9 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA836713LB01HU	SLC38A9 Antibody, HRP conjugated	Human	ELISA
CSB-PA836713LC01HU	SLC38A9 Antibody, FITC conjugated	Human
CSB-PA836713LD01HU	SLC38A9 Antibody, Biotin conjugated	Human	ELISA

SLC38A9 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA600563XA01DIL	slc38a9 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

SLC38A9 Proteins

SLC38A9 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP600563DIL CSB-EP600563DIL CSB-BP600563DIL CSB-MP600563DIL CSB-EP600563DIL-B	Recombinant Danio rerio Putative sodium-coupled neutral amino acid transporter 9 (slc38a9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SLC38A9 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP665484RA CSB-EP665484RA CSB-BP665484RA CSB-MP665484RA CSB-EP665484RA-B	Recombinant Rat Putative sodium-coupled neutral amino acid transporter 9 (Slc38a9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SLC38A9 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP705788XBF CSB-EP705788XBF CSB-BP705788XBF CSB-MP705788XBF CSB-EP705788XBF-B	Recombinant Xenopus tropicalis Putative sodium-coupled neutral amino acid transporter 9 (slc38a9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SLC38A9 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP738541XBE CSB-EP738541XBE CSB-BP738541XBE CSB-MP738541XBE CSB-EP738541XBE-B	Recombinant Xenopus laevis Putative sodium-coupled neutral amino acid transporter 9 (slc38a9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SLC38A9 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP805249MO CSB-EP805249MO CSB-BP805249MO CSB-MP805249MO CSB-EP805249MO-B	Recombinant Mouse Putative sodium-coupled neutral amino acid transporter 9 (Slc38a9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SLC38A9 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-BP836713HU CSB-EP836713HU-B	Recombinant Human Putative sodium-coupled neutral amino acid transporter 9 (SLC38A9), partial	Baculovirus In Vivo Biotinylation in E.coli
CSB-EP836713HU	Recombinant Human Neutral amino acid transporter 9 (SLC38A9),partial	E.coli
CSB-YP836713HU	Recombinant Human Neutral amino acid transporter 9 (SLC38A9),partial	Yeast
CSB-MP836713HU	Recombinant Human Neutral amino acid transporter 9 (SLC38A9), partial	Mammalian cell

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SLC38A9

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