SOCS5 Research Reagents

Suppressor of cytokine signaling 5 is a protein in humans that is encoded by SOCS5 gene. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype.

The following SOCS5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SOCS5 Antibodies

SOCS5 Antibodies for Homo sapiens (Human)

SOCS5 Proteins

SOCS5 Proteins for Homo sapiens (Human)

SOCS5 Proteins for Mus musculus (Mouse)

SOCS5 Proteins for Bos taurus (Bovine)

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