STAM Research Reagents

Signal transducing adapter molecule 1 is a protein in humans that is encoded by STAM gene. Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

The following STAM reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

STAM Antibodies

STAM Antibodies for Homo sapiens (Human)

STAM Proteins

STAM Proteins for Mus musculus (Mouse)

STAM Proteins for Homo sapiens (Human)

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