Signal transducing adapter molecule 1 is a protein in humans that is encoded by STAM gene. Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
The following STAM reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
STAM Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022792GA01HU | STAM Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA620044 | STAM Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA724791 | STAM Antibody |
Human,Mouse | ELISA,IHC |
STAM Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP022792MO CSB-EP022792MO CSB-BP022792MO CSB-MP022792MO CSB-EP022792MO-B |
Recombinant Mouse Signal transducing adapter molecule 1 (Stam) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAM Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP846097HU CSB-EP846097HU CSB-BP846097HU CSB-MP846097HU CSB-EP846097HU-B |
Recombinant Human Signal transducing adapter molecule 1 (STAM) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |