STK4

Serine/threonine-protein kinase 4 is a protein in humans that is encoded by STK4 gene. Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.

The following STK4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

STK4 Antibodies

STK4 Proteins

STK4 Antibodies

STK4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA230165	Phospho-STK4 (Thr183) Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA192084	STK4 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA168071	STK4 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA621644NA01HU	STK4 Antibody	Human	ELISA, IHC, IF
CSB-PA621644NB01HU	STK4 Antibody, HRP conjugated	Human	ELISA
CSB-PA621644NC01HU	STK4 Antibody, FITC conjugated	Human
CSB-PA621644ND01HU	STK4 Antibody, Biotin conjugated	Human	ELISA

STK4 Proteins

STK4 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP022855MOW CSB-EP022855MOW CSB-BP022855MOW CSB-MP022855MOW CSB-EP022855MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP022855ERI CSB-EP022855ERI CSB-BP022855ERI CSB-MP022855ERI CSB-EP022855ERI-B	Recombinant Papio anubis Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey)

Code	Product Name	Source
CSB-YP022855DVH CSB-EP022855DVH CSB-BP022855DVH CSB-MP022855DVH CSB-EP022855DVH-B	Recombinant Colobus guereza Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Code	Product Name	Source
CSB-YP022855DSU CSB-EP022855DSU CSB-BP022855DSU CSB-MP022855DSU CSB-EP022855DSU-B	Recombinant Chlorocebus aethiops Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Aotus nancymaae (Ma's night monkey)

Code	Product Name	Source
CSB-YP022855AUV CSB-EP022855AUV CSB-BP022855AUV CSB-MP022855AUV CSB-EP022855AUV-B	Recombinant Aotus nancymaae Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)

Code	Product Name	Source
CSB-YP022855OFS CSB-EP022855OFS CSB-BP022855OFS CSB-MP022855OFS CSB-EP022855OFS-B	Recombinant Otolemur garnettii Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Lemur catta (Ring-tailed lemur)

Code	Product Name	Source
CSB-YP022855LOK CSB-EP022855LOK CSB-BP022855LOK CSB-MP022855LOK CSB-EP022855LOK-B	Recombinant Lemur catta Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP621644HU CSB-EP621644HU CSB-BP621644HU CSB-MP621644HU CSB-EP621644HU-B	Recombinant Human Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP704835BO CSB-EP704835BO CSB-BP704835BO CSB-MP704835BO CSB-EP704835BO-B	Recombinant Bovine Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP736571CH CSB-EP736571CH CSB-BP736571CH CSB-MP736571CH CSB-EP736571CH-B	Recombinant Chicken Serine/threonine-protein kinase 4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP744043XBF CSB-EP744043XBF CSB-BP744043XBF CSB-MP744043XBF CSB-EP744043XBF-B	Recombinant Xenopus tropicalis Serine/threonine-protein kinase 4 (stk4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP754221XBE CSB-EP754221XBE CSB-BP754221XBE CSB-MP754221XBE CSB-EP754221XBE-B	Recombinant Xenopus laevis Serine/threonine-protein kinase 4 (stk4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Squalus acanthias (Spiny dogfish)

Code	Product Name	Source
CSB-YP773861FKW CSB-EP773861FKW CSB-BP773861FKW CSB-MP773861FKW CSB-EP773861FKW-B	Recombinant Squalus acanthias Serine/threonine-protein kinase 3/4 (STK4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

STK4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP872834MO CSB-EP872834MO CSB-BP872834MO CSB-MP872834MO CSB-EP872834MO-B	Recombinant Mouse Serine/threonine-protein kinase 4 (Stk4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application