TK, or Thymidine Kinase, plays a pivotal role in DNA synthesis. As an enzyme involved in the pyrimidine salvage pathway, it catalyzes the conversion of thymidine (dTdR) into deoxythymidine monophosphate (dTMP). This transformation process makes thymidine the sole entry point in the DNA synthesis pathway, thus TK occupies a crucial position in DNA synthesis, often associated with DNA synthesis and cell cycle regulation. When cells require DNA synthesis, TK is activated and involved in the process. TK may exist in multiple isoenzyme forms in different organisms and tissues, exhibiting distinct structural and functional characteristics. For instance, in human cells, TK appears in two isoenzyme forms: cytosolic thymidine kinase (TK1) and mitochondrial thymidine kinase (TK2), encoded by different genes and playing distinct roles within the cell.
Recombinant Human herpesvirus 1 Thymidine kinase (TK)
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following TK reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TK Proteins for Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
Code | Product Name | Source |
---|---|---|
CSB-YP868748HGAO CSB-EP868748HGAO CSB-BP868748HGAO CSB-MP868748HGAO CSB-EP868748HGAO-B |
Recombinant Human herpesvirus 1 Thymidine kinase (TK) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |