TOMM20

TOMM20, also known as Translocase of Outer Mitochondrial Membrane 20, is a crucial component of the translocase of the outer mitochondrial membrane (TOM) complex. It acts as a receptor on the outer mitochondrial membrane, recognizing and binding to mitochondrial pre - proteins, facilitating their import into the mitochondria. This protein is also commonly referred to as TOM20.
Dysfunction of TOMM20 has been linked to various mitochondrial - related diseases, such as neurodegenerative disorders. In terms of drug development, researchers are exploring compounds that can modulate TOMM20's function to correct mitochondrial protein import defects. This may offer potential therapeutic strategies for related diseases in the future.