TPI1

TPI1, or triphosphate isomerase 1, is an enzyme found in the glycolytic pathway, encoded by the TPI1 gene, and functioning in the cytoplasm. It catalyzes the reversible interconversion of glycerophosphate diphosphate (2- glycerophosphate) and glycerotriphosphate (3- glycerophosphate) during glycolysis, crucial for maintaining intracellular phosphate balance and energy supply. TPI1 is key in cellular energy metabolism, particularly in muscle cells, providing rapid energy during contraction. Its activity and expression levels may be altered in diseases like cancer, implicating a role in tumor metabolism and drawing medical research attention.