Hamartin is a protein in humans that is encoded by TSC1 gene. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
The following TSC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TSC1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025113GA01HU | TSC1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA849764LA01HU | TSC1 Antibody |
Human | ELISA, IHC, IF |
CSB-PA849764LB01HU | TSC1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA849764LC01HU | TSC1 Antibody, FITC conjugated |
Human | |
CSB-PA849764LD01HU | TSC1 Antibody, Biotin conjugated |
Human | ELISA |
TSC1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA790048XA01SXV | tsc1 Antibody |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ELISA, WB (ensure identification of antigen) |
TSC1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP849764HU CSB-BP849764HU CSB-MP849764HU CSB-EP849764HU-B |
Recombinant Human Hamartin (TSC1), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TSC1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP863631MO CSB-EP863631MO CSB-BP863631MO CSB-MP863631MO CSB-EP863631MO-B |
Recombinant Mouse Hamartin (Tsc1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |