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Ubiquitin recognition factor in ER-associated degradation protein 1 is a protein in humans that is encoded by UFD1 gene. Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I
The following UFD1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
UFD1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA025559GA01HU | UFD1L Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA842166ESR1HU | UFD1 Antibody |
Human | ELISA, WB, IHC |
UFD1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA346812XA01SVG | UFD1 Antibody |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ELISA, WB (ensure identification of antigen) |
UFD1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA529791XA01SXV | ufd1 Antibody |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ELISA, WB (ensure identification of antigen) |
UFD1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP025559MO CSB-EP025559MO CSB-BP025559MO CSB-MP025559MO CSB-EP025559MO-B |
Recombinant Mouse Ubiquitin fusion degradation protein 1 homolog (Ufd1l) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UFD1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP346812SVG CSB-EP346812SVG CSB-BP346812SVG CSB-MP346812SVG CSB-EP346812SVG-B |
Recombinant Saccharomyces cerevisiae Ubiquitin fusion degradation protein 1 (UFD1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UFD1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP529791SXV CSB-EP529791SXV CSB-BP529791SXV CSB-MP529791SXV CSB-EP529791SXV-B |
Recombinant Schizosaccharomyces pombe Ubiquitin fusion degradation protein 1 (ufd1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UFD1 Proteins for Dictyostelium discoideum (Slime mold)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP701013DKK CSB-EP701013DKK CSB-BP701013DKK CSB-MP701013DKK CSB-EP701013DKK-B |
Recombinant Dictyostelium discoideum Ubiquitin fusion degradation protein 1 homolog (ufd1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UFD1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP842166HU CSB-BP842166HU CSB-MP842166HU CSB-EP842166HU-B |
Recombinant Human Ubiquitin fusion degradation protein 1 homolog (UFD1L) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP842166HU | Recombinant Human Ubiquitin fusion degradation protein 1 homolog (UFD1L) |
E.coli |
UFD1 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP872139RA CSB-EP872139RA CSB-BP872139RA CSB-MP872139RA CSB-EP872139RA-B |
Recombinant Rat Ubiquitin fusion degradation protein 1 homolog (Ufd1l) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
