WNT2B

WNT2B, or Wnt family member 2B, is a secreted glycoprotein also known by aliases WNT13 and WNT2B1. It acts as a ligand in the canonical Wnt/β-catenin pathway: binding to Frizzled receptors and LRP5/6 co-receptors inhibits β-catenin degradation, enabling its nuclear translocation to regulate genes involved in cell proliferation, differentiation, and tissue morphogenesis.
Dysregulated WNT2B expression links to colorectal, breast, and lung cancers, promoting tumor growth and metastasis. Drug development targeting its pathway includes monoclonal antibodies against Wnt receptors and small-molecule β-catenin inhibitors, though most candidates remain in preclinical or early clinical stages due to pathway complexity and off-target risks.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

WNT2B Antibody (CSB-PA122866)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA122866(WNT2B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Human Protein Wnt-2b(WNT2B) ELISA kit (CSB-EL026134HU)

Validated Data

Code: CSB-EL026134HU

Size: 96T,5×96T,10×96T

Sensitivity: 15.6 pg/mL

Detection Range: 62.5 pg/mL-4000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following WNT2B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

WNT2B Antibodies

WNT2B Proteins

WNT2B ELISA Kits

WNT2B Antibodies

WNT2B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-RA162489A0HU	WNT2B Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF, FC

WNT2B Proteins

WNT2B Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP026134MO CSB-EP026134MO CSB-BP026134MO CSB-MP026134MO CSB-EP026134MO-B	Recombinant Mouse Protein Wnt-2b (Wnt2b), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP856613HU1 CSB-EP856613HU1 CSB-BP856613HU1 CSB-MP856613HU1 CSB-EP856613HU1-B	Recombinant Human Protein Wnt-2b (WNT2B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF856613HU	Recombinant Human Protein Wnt-2b (WNT2B)	in vitro E.coli expression system

WNT2B Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP857835CH CSB-EP857835CH CSB-BP857835CH CSB-MP857835CH CSB-EP857835CH-B	Recombinant Chicken Protein Wnt-2b (WNT2B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2B ELISA Kit

WNT2B ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL026134HU	Human Protein Wnt-2b(WNT2B) ELISA kit	serum, plasma, tissue homogenates, cell lysates	15.6 pg/mL

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WNT2B

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