Protein KIBRA is a protein in humans that is encoded by WWC1 gene. Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
The following WWC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
WWC1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
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CSB-YP026163XBF CSB-EP026163XBF CSB-BP026163XBF CSB-MP026163XBF CSB-EP026163XBF-B |
Recombinant Xenopus tropicalis Protein KIBRA (wwc1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WWC1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
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CSB-YP729193MO CSB-EP729193MO CSB-BP729193MO CSB-MP729193MO CSB-EP729193MO-B |
Recombinant Mouse Protein KIBRA (Wwc1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WWC1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
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CSB-YP812885HU CSB-EP812885HU CSB-BP812885HU CSB-MP812885HU CSB-EP812885HU-B |
Recombinant Human Protein KIBRA (WWC1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |