WWC1 Research Reagents

Protein KIBRA is a protein in humans that is encoded by WWC1 gene. Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

The following WWC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

WWC1 Proteins

WWC1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

WWC1 Proteins for Mus musculus (Mouse)

WWC1 Proteins for Homo sapiens (Human)

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