Zinc Finger Protein 395 (ZNF395), a C2H2-type zinc finger protein, functions as a transcription regulator. It binds specific DNA sequences via its zinc finger domains to modulate target gene expression, participating in pathways like Wnt/β-catenin that control cell proliferation and differentiation.
Dysregulated ZNF395 expression is linked to cancers such as hepatocellular carcinoma and lung adenocarcinoma, where it may act as an oncogene or tumor suppressor. Currently, no targeted drugs against ZNF395 are in clinical use, but preclinical studies explore its potential as a diagnostic biomarker and therapeutic target for cancer treatment.
Recombinant Human Zinc finger protein 395 (ZNF395) (CSB-EP026718HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ZNF395 Antibody (CSB-PA151926)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA151926(ZNF395 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following ZNF395 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ZNF395 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA026718GA01HU | ZNF395 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA151926 | ZNF395 Antibody | Human | ELISA,IHC |
ZNF395 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP026718HU CSB-BP026718HU CSB-MP026718HU CSB-EP026718HU-B |
Recombinant Human Zinc finger protein 395 (ZNF395) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP026718HU | Recombinant Human Zinc finger protein 395 (ZNF395) | E.coli |