gfap Research Reagents

Glial fibrillary acidic protein (GFAP) is a class III intermediate filament (IFs) specifically expressed in the cytoplasm of central nervous system astrocytes (AS). It acts as an astrocyte-specific marker.

Glial fibrous acidic protein is found in the brains of people with multiple sclerosis (MS).The GFAP gene was subsequently cloned in mouse and human.

The GFAP gene has alternative splicing, which causes multiple transcriptional variants to encode different protein subtypes. Ten GFAP splicing isomers are known to be expressed in the nervous systems of mouse and human. There are a total of 10 GFAP splice isoforms expressed in the mouse and human nervous systems: GFAP GFAPα, β, γ, δ, ζ, κ, ∆exon 7, ∆135, ∆164, ∆exon6 and ∆exon 7.

GFAP is involved in intracellular cytoskeletal reorganization, cell adhesion, maintenance of myelination and neuronal structure in the brain, involvement in the formation of the blood-brain barrier, and regulation of synapses. It is also involved in cell migration, movement and mitosis.

This article shows the details of GFAP: Glial Fibrillary Acidic Protein - Astrocyte Specific Marker.

Astrocytes are involved in a variety of central nervous system diseases, including trauma, ischemia, and neurodegeneration.

If you are involved in research on neurological diseases, you may need GFAP related products. CUSABIO offers a variety of GFAP-related products, including ELISA kits, antibodies, proteins, and small molecule products.

A GFAP Monoclonal Antibody, CSB-MA009369A0m, which I will recommend to you. It has many applications: ELISA, WB, IHC, IF and FC. It can be used in multiple species, mainly including Human, Mouse and Rat.

The following gfap reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.