Recombinant Mouse Interleukin-3 protein(Il3) (Active)

Code CSB-AP003291MO
Product Type Interleukin
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P01586
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2x107 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence DTHRLTRTLN CSSIVKEIIG KLPEPELKTD DEGPSLRNKS FRRVNLSKFV ESQGEVDPED RYVIKSNLQK LNCCLPTSAN DSALPGVFIR DLDDFRKKLR FYMVHLNDLE TVLTSRPPQP ASGSVSPNRG TVEC
Research Area Immunology
Source E.Coli
Gene Names Il3
Expression Region 33-166aa
Product Info Tag-Free
Mol. Weight 14.8 kDa
Protein Description Partial
PubMed ID 6420702; 6322187; 3918308; 3926497; 3935516; 1445902; 21329364
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Function Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; FUNCTION
Subcellular location Secreted
Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Fc epsilon RI signaling pathway
Hematopoietic cell lineage

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