Recombinant Human Coagulation factor XI(F11),partial

In Stock
Code CSB-EP007916HU
Product Type Recombinant Protein
Size US$2466Purchase it in Cusabio online store
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Uniprot No. P03951
Lead Time 3-7 business days
Relevance Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Plasma thromboplastin antecedent Short name:PTA Cleaved into the following 2 chains: Coagulation factor XIa heavy chain Coagulation factor XIa light chain
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Research Area Cardiovascular
Source E.coli
Gene Names F11
Protein Names Recommended name: Coagulation factor XI Short name= FXI EC= Alternative name(s): Plasma thromboplastin antecedent Short name= PTA Cleaved into the following 2 chains: 1. Coagulation factor XIa heavy chain 2.
Expression Region 19-387aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 45.2kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Involvement in disease Factor XI deficiency (FA11D)
Subcellular Location Secreted
Protein Families Peptidase S1 family, Plasma kallikrein subfamily
Tissue Specificity Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.
Database Links

HGNC: 3529

OMIM: 264900

KEGG: hsa:2160

STRING: 9606.ENSP00000384957

UniGene: Hs.1430

Pathway Complement and coagulation cascades

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