Code | CSB-RA101461A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The PIK3R1 recombinant monoclonal antibody is generated using in vitro expression systems developed by cloning the DNA sequences of PIK3R1 antibodies from immunoreactive rabbits. The immunogen used in this process is a synthesized peptide derived from the human PIK3R1 protein. Subsequently, the genes encoding the PIK3R1 antibodies are inserted into plasmid vectors, and these recombinant plasmid vectors are transfected into host cells to facilitate the expression of the antibody. Following expression, the PIK3R1 recombinant monoclonal antibody undergoes affinity-chromatography purification. It is rigorously tested for functionality in ELISA and IHC applications, demonstrating reactivity with the human PIK3R1 protein during these laboratory evaluations.
PIK3R1 is a critical regulatory protein that plays a central role in controlling the PI3K signaling pathway. This pathway influences a wide range of cellular functions, including cell growth, proliferation, survival, metabolism, and immune responses. Dysregulation of PIK3R1 or the PI3K pathway can have significant implications in various diseases, including cancer and metabolic disorders.
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