Monoclonal Antibody Drugs OverviewIn 1982, Humulin (human insulin), the world's first recombinant drug, was approved for marketing. This is a milestone in the development of drug access from chemical synthesis or extraction of Chinese medicine to biotech...
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SLC39A6/ZIP6: a Key Member of Zinc Transporters, a Novel Targeting Antigen of ADC!Presently, ADC competition heats up in global biotech or pharmaceuticals companies. According to the Pharmsnap database, there are nearly 100 partnered or licensed deals based on ADC new drugs, which has an estimated val...
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What You Have To Know about Lung CancerLung cancer is the leading cause of cancer deaths in both men and women in the U.S. and worldwide. It claims more lives each year than do colon, prostate, ovarian and breast cancers combined, and the cause of lung cancer...
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TMEFF2: a Tumor-Specific Methylated Biomarker, a Novel Target in Multiple CancersThe European Society for Medical Oncology (ESMO) Congress 2022 was held in Paris, 9-13 September 2022. As the most influential oncology platform for clinicians and researchers globally, the event brings the new opportuni...
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CD93, A Rising Star in Anti-Tumor TherapyIn August this year, Jia et al., from the School of Life and Pharmacy of the Dalian University of Technology, published a paper entitled "CD93 Promotes Acute Myoid Leukemia Development and IS A Potential Therapeutic Targ...
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CD20 Monoclonal Antibodies Drugs: There is an Explosion of New mAbs Against CD20!On August 23, 2022, Sinocelltech Group Ltd. from China's NMPA has received marketing approval for its recombinant chimeric anti-CD20 monoclonal antibody--Ripertamab (SCT-400), to treat patients with CD20-positive diffuse...
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Get An Overview of His-TagIn analyzing the structure and function of recombinant proteins, the most important thing is to get pure recombinant proteins. Therefore, various methods have been explored to isolate high-purity recombinant proteins. Am...
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Nanoparticle platformIt is difficult for small molecular weight proteins to generate an immune response due to their small molecular weight. Although the fusion of large tags can enhance the immune response, the structure of the target prote...
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Protein Tyrosine Kinases: Anti-tumor Targets to be Explored UrgentlyIn 2001, the first kinase inhibitor imatinib was approved by the FDA and successfully marketed, representing an important breakthrough of kinase drugs in the field of molecular targeted cancer treatment. Recently, an art...
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Tuberculosis--A Resurgent As World Tuberculosis Day on March 24 approaches, I would like to take this opportunity to discuss tuberculosis, a major global public health threat that still persists. According to the World Health Organizati...
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