How Do You Get Exosomes?
How Do You Get Exosomes?Exosomes were originally regarded as cellular metabolic waste. With the discovery of the antigen-presenting exosomes secreted by B lymphocytes involving anti-tumor responses in 1996 [1]and the exchange of genetic materia...
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How to Inquire and Utilize the Signal Pathway on KEGG
How to Inquire and Utilize the Signal Pathway on KEGGThe signal pathway was first known as signal transmission. M. Rodbell proposed the concept of signal transduction in 1980 and has since been widely used. Signaling pathways refer to a series of enzymatic reactio...
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CD146, A Powerful Tumor Marker
CD146, A Powerful Tumor MarkerCD146 is a membrane glycoprotein of a Ca2+-independent cell adhesion molecule that was first identified as a tumor marker because CD146 is highly expressed in melanoma but not in the corresponding normal control group. I...
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About Thyroid Tumor, This Information You Must Know!
About Thyroid Tumor, This Information You Must Know!The thyroid gland is part of the endocrine system and is a hormone-producing gland that regulates the body's functions. Thyroid cancer (TC), which occurs in thyroid cells, is the most common endocrine - related cancer, a...
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Mesothelin: A Rising Star of Cancer Immunotherapy
Mesothelin: A Rising Star of Cancer ImmunotherapyMesothelin, also known as MSLN, is a cell surface glycoprotein encoded by the MSLN gene. The MSLN gene encodes a precursor protein that is enzymatically decomposed into two products: megakaryocyte-potentiating factor (MP...
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OMA1-A Potential Cancer Therapy Target
OMA1-A Potential Cancer Therapy TargetThe mitochondria are double-membrane-bound organelles found in most eukaryotic organisms and are the main energizing organelles of cells. The most prominent roles of mitochondria are to produce the energy currency of the...
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EphA3-A Regulator of Cell Adhesion and Migration
EphA3-A Regulator of Cell Adhesion and MigrationReceptor tyrosine kinase (RTKs) is a type I transmembrane glycoprotein that regulates cell growth, differentiation and migration. The Eph receptor family (erythropoietin-producing human hepatocellular carcinoma) is the l...
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Ovarian Cancer -- The Silent Killer
Ovarian Cancer -- The Silent KillerThe ovaries are the female reproductive organs that produce eggs. Ovarian cancer refers to the cancerous changes that occur in the ovaries. It is a tumor caused by abnormal, uncontrollable reproduction of certain cells i...
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Growth Hormone - Not Only Promotes Height Increase
Growth Hormone - Not Only Promotes Height IncreaseGrowth hormone 1, also known as somatotropin, or growth hormone (GH). It is a member of the growth hormone/prolactin family. It is a single peptide chain protein hormone secreted by pituitary gland. The role of this horm...
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TROP2-An Important Target for Cancer Treatment
TROP2-An Important Target for Cancer TreatmentTROP2 belongs to the TACSTD family and is a cell surface glycoprotein encoded by the TACSTD2 gene. It is also known as tumor-associated calcium signal transducer 2 (TACSTD2), epidermal glycoprotein 1 (EGP-1), and gastroi...
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