ADIPOR1 encodes the adiponectin receptor 1, also commonly known as ADIPOR1. This protein is crucial in the body's metabolic regulation. It binds with adiponectin, an adipokine, and activates multiple downstream signaling pathways like the AMPK pathway, enhancing fatty - acid oxidation and glucose uptake in skeletal muscles.
Dysregulation of ADIPOR1 is associated with various diseases, including type 2 diabetes and obesity. Given its significant role, ADIPOR1 has become a promising target for drug development. Some pre - clinical studies are exploring agonists to improve insulin sensitivity and metabolic function, aiming to address related metabolic disorders.
Recombinant Human Adiponectin receptor protein 1 (ADIPOR1), partial (CSB-CF001367HU2)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ADIPOR1 Antibody (CSB-PA001367LA01HU)
Validated Data
Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: ADIPOR1 antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa
Western Blot
Positive WB detected in: K562 whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate
All lanes: ADIPOR1 antibody at 1:2500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001367LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA001367LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following ADIPOR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ADIPOR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA226584 | ADIPOR1 Antibody | Human,Mouse | ELISA,WB |
CSB-PA562872 | ADIPOR1 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA001367LA01HU | ADIPOR1 Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA001367LD01HU | ADIPOR1 Antibody, Biotin conjugated | Human | ELISA |
ADIPOR1 Antibodies for Oryza sativa subsp. japonica (Rice)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA228779XA01OFG | ADIPOR1 Antibody | Oryza sativa subsp. japonica (Rice) | ELISA, WB (ensure identification of antigen) |
ADIPOR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF842016MO | Recombinant Mouse Adiponectin receptor protein 1 (Adipor1) | in vitro E.coli expression system |
CSB-YP842016MO1 CSB-EP842016MO1 CSB-BP842016MO1 CSB-MP842016MO1 CSB-EP842016MO1-B |
Recombinant Mouse Adiponectin receptor protein 1 (Adipor1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADIPOR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF001367HU | Recombinant Human Adiponectin receptor protein 1 (ADIPOR1) | in vitro E.coli expression system |
CSB-YP856893HU CSB-EP856893HU CSB-BP856893HU CSB-MP856893HU CSB-EP856893HU-B |
Recombinant Human Adiponectin receptor protein 1 (ADIPOR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF001367HU2 | Recombinant Human Adiponectin receptor protein 1 (ADIPOR1), partial | in vitro E.coli expression system |
CSB-CF001367HU2e1 | Recombinant Human Adiponectin receptor protein 1 (ADIPOR1), partial | in vitro E.coli expression system |
CSB-MP001367HU | Recombinant Human Adiponectin receptor protein 1 (ADIPOR1)-VLPs | Mammalian cell |