AIMP2, also known as aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, is an essential component of the multi - aminoacyl - tRNA synthetase complex. Common aliases include p38. It plays a key role in protein synthesis by catalyzing the ligation of amino acids to their cognate tRNAs. It is also involved in various cellular processes through its interaction with other proteins.
AIMP2 is associated with the JAK - STAT signaling pathway. Dysregulation of AIMP2 has been implicated in several diseases, such as cancer and neurodegenerative disorders. In drug development, researchers are exploring small - molecule drugs targeting AIMP2 to modulate its function for therapeutic purposes, though significant progress is still awaited.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
AIMP2 Antibody (CSB-PA819153ESR1HU)
Validated Data
Western blot
All lanes: AIMP2 antibody at 5μg/ml
Lane 1: Hela whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA819153ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA819153ESR1HU at dilution of 1:100
The following AIMP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
AIMP2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA819153ESR1HU | AIMP2 Antibody | Human | ELISA, WB, IHC |
CSB-PA151818 | AIMP2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA289421 | AIMP2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA904906 | AIMP2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
AIMP2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618761HU CSB-BP618761HU CSB-MP618761HU CSB-EP618761HU-B |
Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP618761HU | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) | E.coli |