ALKBH5

ALKBH5, also known as RNA demethylase ALKBH5, is a protein that plays a crucial role in regulating mRNA methylation. It functions by demethylating N6-methyladenosine (m6A) from mRNA, which is essential for gene expression and translation. ALKBH5 is involved in various signaling pathways, including those related to osteogenic differentiation. The protein is associated with several diseases, such as gastric cancer, renal cell cancer, and breast cancer. In terms of drug development, selective inhibitors of ALKBH5, like TD19, have been identified, which could potentially be used in anticancer research.