AQPZ

AqpZ, found in Escherichia coli's K12 strain, is a protein that assembles into functional tetramers on the cell's inner membrane, acting as water channels. These channels facilitate the bidirectional flow of water, influenced by permeability. Noted for its high water permeability and structural stability, AqpZ efficiently moves water molecules across the membrane while keeping out other small molecules and ions. The key residue Arg-189 is central to its selective filtration and channel operation, modulating the flow through side chain movements. This protein is essential for cellular osmotic balance and holds promise for applications in water recovery and desalination technologies.