Acid-sensing ion channel 3 is a protein in humans that is encoded by ASIC3 gene. Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
The following ASIC3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ASIC3 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application | 
|---|---|---|---|
| CSB-PA005120 | ASIC3 Antibody | Human | WB, ELISA | 
| CSB-PA890688ESR1HU | ASIC3 Antibody | Human | ELISA, WB, IHC | 
ASIC3 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source | 
|---|---|---|
| CSB-YP754454MO CSB-EP754454MO CSB-BP754454MO CSB-MP754454MO CSB-EP754454MO-B | Recombinant Mouse Acid-sensing ion channel 3 (Asic3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli | 
ASIC3 Proteins for Homo sapiens (Human)
| Code | Product Name | Source | 
|---|---|---|
| CSB-YP890688HU CSB-EP890688HU CSB-BP890688HU CSB-MP890688HU CSB-EP890688HU-B | Recombinant Human Acid-sensing ion channel 3 (ASIC3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli | 
ASIC3 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source | 
|---|---|---|
| CSB-YP001143RA CSB-EP001143RA CSB-BP001143RA CSB-MP001143RA CSB-EP001143RA-B | Recombinant Rat Acid-sensing ion channel 3 (Asic3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |