ASPA, or aspartase, is a protein with multiple functions in living organisms.Discovered in 1975 by researchers at the International Thermal Conductivity Corporation in Japan, ASPA has a molecular weight of 21.1 kDa and consists of two equal polypeptide chains containing 10 amino acids. It is involved in a variety of biological processes such as promoting cell proliferation, inducing apoptosis, regulating the cell cycle and participating in cell signalling. In oncology research, ASPA has been used as a drug target that interacts with proteins in tumour cells to inhibit the growth and spread of tumour cells .ASPA has a wide range of applications in drug discovery, and can be used as a drug target for the treatment of cancer, for example, drugs that inhibit the activity of ASPA can inhibit the growth and spread of cancer cells . In addition, ASPA can be used as a biomarker to detect the extent of disease and the effectiveness of treatment. In a biological sense, the activity and expression level of ASPA is closely related to the development of many diseases, and is an important target in medical research and treatment.
Recombinant Human Aspartoacylase (ASPA) (CSB-YP002223HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue, human fetal kidney tissue, Primary antibody: CSB-PA790667(ASPA Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
The following ASPA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ASPA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA002223GA01HU | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA790667 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA075666 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA002223ZA01HU | ASPA Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
ASPA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP002223HU | Recombinant Human Aspartoacylase (ASPA) | Yeast |
CSB-EP002223HU | Recombinant Human Aspartoacylase (ASPA) | E.coli |
CSB-BP002223HU | Recombinant Human Aspartoacylase (ASPA) | Baculovirus |
CSB-MP002223HU | Recombinant Human Aspartoacylase (ASPA) | Mammalian cell |