CD2

CD2, also recognized as Tp44 or LFA-2, is a cell surface glycoprotein encoded by the CD2 gene and part of the immunoglobulin superfamily. Predominantly found on mature T cells and some NK cells, CD2 engages with extracellular ligands like CD58 to facilitate T cell activation, proliferation, and immune synapse formation, thereby regulating interactions with other immune cells. Its dysfunction has been implicated in autoimmune diseases and immunodeficiencies, with CD2 gene mutations potentially leading to immunodeficiency, highlighting CD2 as a significant target for immunological research and therapeutics.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD2 Antibody (CSB-PA004894LA01HU)

Validated Data

Immunofluorescence staining of Hela cells with CSB-PA004894LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004894LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004894LA01HU at dilution of 1:100

The following CD2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CD2 Antibodies

CD2 Proteins

CD2 Antibodies

CD2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA004894GA01HU	CD2 Antibody	Human	ELISA,WB
CSB-PA004894LA01HU	CD2 Antibody	Human	ELISA, IHC, IF
CSB-PA004894LB01HU	CD2 Antibody, HRP conjugated	Human	ELISA
CSB-MA000227	CD2 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA005194	CD2 Antibody	Human	WB, ELISA

CD2 Proteins

CD2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP004894HU CSB-BP004894HU CSB-EP004894HU-B	Recombinant Human T-cell surface antigen CD2 (CD2), partial	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP004894HU	Recombinant Human T-cell surface antigen CD2 (CD2), partial	E.coli
CSB-CF004894HU	Recombinant Human T-cell surface antigen CD2 (CD2)	in vitro E.coli expression system
CSB-CF004894HU(A4)	Recombinant Human T-cell surface antigen CD2 (CD2)	in vitro E.coli expression system
CSB-MP004894HU(A4)f4	Recombinant Human T-cell surface antigen CD2 (CD2)-VLPs, Fluorescent	Mammalian cell

CD2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP750970MOV CSB-EP750970MOV CSB-BP750970MOV CSB-MP750970MOV CSB-EP750970MOV-B	Recombinant Macaca fascicularis T-cell surface antigen CD2 (CD2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CD2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-CF004894RA	Recombinant Rat T-cell surface antigen CD2 (Cd2)	in vitro E.coli expression system
CSB-YP004894RA1 CSB-EP004894RA1 CSB-BP004894RA1 CSB-MP004894RA1 CSB-EP004894RA1-B	Recombinant Rat T-cell surface antigen CD2 (Cd2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CD2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF004894MO	Recombinant Mouse T-cell surface antigen CD2 (Cd2)	in vitro E.coli expression system
CSB-YP004894MO1 CSB-EP004894MO1 CSB-BP004894MO1 CSB-MP004894MO1 CSB-EP004894MO1-B	Recombinant Mouse T-cell surface antigen CD2 (Cd2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CD2 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-CF004894HO	Recombinant Horse T-cell surface antigen CD2 (CD2)	in vitro E.coli expression system
CSB-YP004894HO1 CSB-EP004894HO1 CSB-BP004894HO1 CSB-MP004894HO1 CSB-EP004894HO1-B	Recombinant Horse T-cell surface antigen CD2 (CD2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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CD2

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