CD2, also recognized as Tp44 or LFA-2, is a cell surface glycoprotein encoded by the CD2 gene and part of the immunoglobulin superfamily. Predominantly found on mature T cells and some NK cells, CD2 engages with extracellular ligands like CD58 to facilitate T cell activation, proliferation, and immune synapse formation, thereby regulating interactions with other immune cells. Its dysfunction has been implicated in autoimmune diseases and immunodeficiencies, with CD2 gene mutations potentially leading to immunodeficiency, highlighting CD2 as a significant target for immunological research and therapeutics.
Recombinant Human T-cell surface antigen CD2 (CD2), partial (CSB-EP004894HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CD2 Antibody (CSB-PA004894LA01HU)
Validated Data
Immunofluorescence staining of Hela cells with CSB-PA004894LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004894LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004894LA01HU at dilution of 1:100
The following CD2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CD2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004894GA01HU | CD2 Antibody | Human | ELISA,WB |
CSB-PA004894LA01HU | CD2 Antibody | Human | ELISA, IHC, IF |
CSB-PA004894LB01HU | CD2 Antibody, HRP conjugated | Human | ELISA |
CSB-MA000227 | CD2 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA005194 | CD2 Antibody | Human | WB, ELISA |
CD2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP004894HU CSB-BP004894HU CSB-EP004894HU-B |
Recombinant Human T-cell surface antigen CD2 (CD2), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-EP004894HU | Recombinant Human T-cell surface antigen CD2 (CD2), partial | E.coli |
CSB-CF004894HU | Recombinant Human T-cell surface antigen CD2 (CD2) | in vitro E.coli expression system |
CSB-CF004894HU(A4) | Recombinant Human T-cell surface antigen CD2 (CD2) | in vitro E.coli expression system |
CSB-MP004894HU(A4)f4 | Recombinant Human T-cell surface antigen CD2 (CD2)-VLPs, Fluorescent | Mammalian cell |
CD2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Code | Product Name | Source |
---|---|---|
CSB-YP750970MOV CSB-EP750970MOV CSB-BP750970MOV CSB-MP750970MOV CSB-EP750970MOV-B |
Recombinant Macaca fascicularis T-cell surface antigen CD2 (CD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF004894RA | Recombinant Rat T-cell surface antigen CD2 (Cd2) | in vitro E.coli expression system |
CSB-YP004894RA1 CSB-EP004894RA1 CSB-BP004894RA1 CSB-MP004894RA1 CSB-EP004894RA1-B |
Recombinant Rat T-cell surface antigen CD2 (Cd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF004894MO | Recombinant Mouse T-cell surface antigen CD2 (Cd2) | in vitro E.coli expression system |
CSB-YP004894MO1 CSB-EP004894MO1 CSB-BP004894MO1 CSB-MP004894MO1 CSB-EP004894MO1-B |
Recombinant Mouse T-cell surface antigen CD2 (Cd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD2 Proteins for Equus caballus (Horse)
Code | Product Name | Source |
---|---|---|
CSB-CF004894HO | Recombinant Horse T-cell surface antigen CD2 (CD2) | in vitro E.coli expression system |
CSB-YP004894HO1 CSB-EP004894HO1 CSB-BP004894HO1 CSB-MP004894HO1 CSB-EP004894HO1-B |
Recombinant Horse T-cell surface antigen CD2 (CD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |