COX4I1

Cytochrome c oxidase subunit 4 isoform 1 (COX4I1), commonly known as COXIV-1, is a core subunit of mitochondrial respiratory chain complex IV. It facilitates electron transfer from cytochrome c to molecular oxygen during oxidative phosphorylation, a process critical for ATP production and cellular energy homeostasis.
COX4I1 is involved in pathways regulating mitochondrial function and stress responses. Dysregulation of its expression links to mitochondrial disorders like Leigh syndrome and cancer, where altered energy metabolism supports tumor growth. Preclinical studies explore its potential as a therapeutic target for metabolic and neoplastic diseases, though clinical drug development remains in early stages.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

COX4I1 Antibody (CSB-PA00509A0Rb)

Validated Data

Western blot
All lanes: COX4I1 antibody at 10µg/ml
Lane 1: Rat muscle tissue
Lane 2: Zebrafish lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA00509A0Rb at dilution of 1:100

The following COX4I1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

COX4I1 Antibodies

COX4I1 Proteins

COX4I1 Antibodies

COX4I1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA00509A0Rb	COX4I1 Antibody	Human, Rat, Zebrafish	ELISA, WB, IHC
CSB-PA005832GA01HU	COX4I1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA096967	COX4I1 Antibody	Human	ELISA,WB,IHC
CSB-PA005832ESR1HU	COX4I1 Antibody	Human	ELISA, WB, IHC
CSB-MA000188	COX4I1 Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA001765	COX4I1 Antibody	Human	WB, IHC, IF, ELISA
CSB-PA080145	COX4I1 Antibody	Human,Mouse,Rat	WB, IHC
CSB-PA246804	COX4I1 Antibody	Human	ELISA,IHC
CSB-PA579290	COX4I1 Antibody	Human	ELISA,IHC

COX4I1 Proteins

COX4I1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005832HU CSB-BP005832HU CSB-MP005832HU CSB-EP005832HU-B	Recombinant Human Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP005832HU	Recombinant Human Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	E.coli

COX4I1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP005832MO CSB-EP005832MO CSB-BP005832MO CSB-MP005832MO CSB-EP005832MO-B	Recombinant Mouse Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cox4i1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP523700GGZ CSB-EP523700GGZ CSB-BP523700GGZ CSB-MP523700GGZ CSB-EP523700GGZ-B	Recombinant Gorilla gorilla gorilla Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Hylobates agilis (Agile gibbon)

Code	Product Name	Source
CSB-YP524306HXV CSB-EP524306HXV CSB-BP524306HXV CSB-MP524306HXV CSB-EP524306HXV-B	Recombinant Hylobates agilis Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Perodicticus potto edwarsi (Potto)

Code	Product Name	Source
CSB-YP524307ETS CSB-EP524307ETS CSB-BP524307ETS CSB-MP524307ETS CSB-EP524307ETS-B	Recombinant Perodicticus potto edwarsi Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Saimiri ustus (Golden-backed squirrel monkey)

Code	Product Name	Source
CSB-YP524308SWE CSB-EP524308SWE CSB-BP524308SWE CSB-MP524308SWE CSB-EP524308SWE-B	Recombinant Saimiri ustus Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Saimiri sciureus (Common squirrel monkey)

Code	Product Name	Source
CSB-YP525030SWD CSB-EP525030SWD CSB-BP525030SWD CSB-MP525030SWD CSB-EP525030SWD-B	Recombinant Saimiri sciureus Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Sapajus apella (Brown-capped capuchin) (Cebus apella)

Code	Product Name	Source
CSB-YP525031DQU CSB-EP525031DQU CSB-BP525031DQU CSB-MP525031DQU CSB-EP525031DQU-B	Recombinant Cebus apella Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP526151EQV CSB-EP526151EQV CSB-BP526151EQV CSB-MP526151EQV CSB-EP526151EQV-B	Recombinant Pan troglodytes Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)

Code	Product Name	Source
CSB-YP526152TOY CSB-EP526152TOY CSB-BP526152TOY CSB-MP526152TOY CSB-EP526152TOY-B	Recombinant Trachypithecus cristatus Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Aotus azarae (Southern owl monkey) (Aotus azarai)

Code	Product Name	Source
CSB-YP527378DNH CSB-EP527378DNH CSB-BP527378DNH CSB-MP527378DNH CSB-EP527378DNH-B	Recombinant Aotus azarae Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Theropithecus gelada (Gelada baboon)

Code	Product Name	Source
CSB-YP528614TNU CSB-EP528614TNU CSB-BP528614TNU CSB-MP528614TNU CSB-EP528614TNU-B	Recombinant Theropithecus gelada Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Mandrillus sphinx (Mandrill) (Papio sphinx)

Code	Product Name	Source
CSB-YP528615MPU CSB-EP528615MPU CSB-BP528615MPU CSB-MP528615MPU CSB-EP528615MPU-B	Recombinant Mandrillus sphinx Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Pongo pygmaeus (Bornean orangutan)

Code	Product Name	Source
CSB-YP529833EXP CSB-EP529833EXP CSB-BP529833EXP CSB-MP529833EXP CSB-EP529833EXP-B	Recombinant Pongo pygmaeus Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Pithecia pithecia (White-faced saki)

Code	Product Name	Source
CSB-YP529834EWG CSB-EP529834EWG CSB-BP529834EWG CSB-MP529834EWG CSB-EP529834EWG-B	Recombinant Pithecia pithecia Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP846460PI CSB-EP846460PI CSB-BP846460PI CSB-MP846460PI CSB-EP846460PI-B	Recombinant Pig Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP871324RB CSB-EP871324RB CSB-BP871324RB CSB-MP871324RB CSB-EP871324RB-B	Recombinant Rabbit Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COX4I1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF005832BO	Recombinant Bovine Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	in vitro E.coli expression system
CSB-YP005832BO1 CSB-EP005832BO1 CSB-BP005832BO1 CSB-MP005832BO1 CSB-EP005832BO1-B	Recombinant Bovine Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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