E6 typically refers to the protein of HPV (Human Papillomavirus), which possesses oncogenic properties. The E6 protein of HPV has multiple subtypes but generally exhibits two key characteristics: the ability to bind to specific proteins within host cells, such as those involved in cell cycle regulation, and the capability to degrade certain proteins within the cell. The binding of the E6 protein to specific proteins in host cells, such as the p53 protein, often leads to the degradation of these proteins. When the E6 protein binds to p53 and leads to its degradation, cells lose control over abnormal cell growth, potentially resulting in uncontrolled proliferation. Research on the E6 protein is crucial in understanding the mechanisms behind cancer development caused by HPV infection, tumor formation, and cancer treatment. This understanding can aid in developing preventive and therapeutic methods for HPV-related cancers and contribute to a deeper comprehension of the process of cancer progression.
Recombinant Human papillomavirus type 16 Protein E6 (E6)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP365854HML could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) E6.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP365854HML could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) E6.
The following E6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
E6 Antibodies for Human papillomavirus type 16
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA365854LA01HML | E6 Antibody |
Human papillomavirus type 16 | ELISA |
CSB-PA365854LB01HML | E6 Antibody, HRP conjugated |
Human papillomavirus type 16 | ELISA |
CSB-PA365854LC01HML | E6 Antibody, FITC conjugated |
Human papillomavirus type 16 | |
CSB-PA365854LD01HML | E6 Antibody, Biotin conjugated |
Human papillomavirus type 16 | ELISA |
E6 Proteins for Human papillomavirus type 16
Code | Product Name | Source |
---|---|---|
CSB-EP365854HML | Recombinant Human papillomavirus type 16 Protein E6 (E6) |
E.coli |
CSB-YP365854HML | Recombinant Human papillomavirus type 16 Protein E6 (E6) |
Yeast |
CSB-BP365854HML CSB-MP365854HML CSB-EP365854HML-B |
Recombinant Human papillomavirus type 16 Protein E6 (E6) |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
E6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP365854HMLg5 | Recombinant Human papillomavirus type 16 Protein E6 (E6) |
E.coli |