Fibulin-7 (FBLN7), a secreted glycoprotein of the fibulin family, has no widely recognized alternative aliases. It contributes to extracellular matrix (ECM) assembly by interacting with laminin-111 and collagen IV—core components of basement membranes—thus supporting tissue structural integrity and regulating cell-matrix adhesion.
Dysregulation of FBLN7 is associated with renal fibrosis and ovarian cancer (where its expression is reduced). It crosstalks with TGF-β signaling, a central pathway in fibrotic processes. Preclinical research focuses on modulating FBLN7’s ECM interactions to develop therapies for fibrotic disorders like chronic kidney disease, though no clinical-stage drugs exist yet.
Recombinant Human Fibulin-7 (FBLN7) (CSB-EP687502HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FBLN7 Antibody (CSB-PA687502LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA687502LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA687502LA01HU at dilution of 1:100
Human Fibulin-7(FBLN7) ELISA kit (CSB-EL008455HU)
Validated Data
Code: CSB-EL008455HU
Size: 96T,5×96T,10×96T
Sensitivity: 6.25 pg/mL
Detection Range: 25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following FBLN7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FBLN7 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA687502LA01HU | FBLN7 Antibody | Human | ELISA, IHC |
| CSB-PA687502LB01HU | FBLN7 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA687502LC01HU | FBLN7 Antibody, FITC conjugated | Human | |
| CSB-PA687502LD01HU | FBLN7 Antibody, Biotin conjugated | Human | ELISA |
FBLN7 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP687502HU CSB-MP687502HU CSB-EP687502HU-B |
Recombinant Human Fibulin-7 (FBLN7) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP687502HU | Recombinant Human Fibulin-7 (FBLN7) | E.coli |
FBLN7 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL008455HU | Human Fibulin-7(FBLN7) ELISA kit | serum, plasma, tissue homogenates | 6.25 pg/mL |